GM Free Cymru

Glyphosate Studies relevant to Human Health

Date Added to website 13th August 2014


This is an updated list. Grateful thanks to GMOFree USA. Source:


Arbuckle, T.E.; Lin, Z.& Mery, L.S. (2001). An exploratory analysis of the effect of pesticide exposure on the risk of spontaneous abortion in an Ontario farm population. Environmental Health Perspectives, 109, 851-857.

K.L. Bassil, MSc, C. Vakil, MD CCFP FCFP, M. Sanborn, MD CCFP FCFP, D.C. Cole, MD MSc FRCPC, J.S. Kaur, MD, K.J. Kerr, MD DIP ENV HEALTH (2007) Cancer health effects of pesticides Can Fam Physician. October; 53(10): 17041711.

Benachour N, Sipahutar H, Moslemi S, Gasnier C, Travert C, Sralini GE. (2007) Time- and dose-dependent effects of roundup on human embryonic and placental cells. Arch Environ Contam Toxicol. Jul;53(1):126-33

Benachour N, Sralini GE. (2009) Glyphosate formulations induce apoptosis and necrosis in human umbilical, embryonic, and placental cells. Chem Res Toxicol. Jan;22(1):97-105.

Benedetti D, Nunes E, Sarmento M, Porto C, Dos Santos CE, Dias JF, da Silva J. (2013) Genetic damage in soybean workers exposed to pesticides: evaluation with the comet and buccal micronucleus cytome assays. Mutat Res. Apr 15;752(1-2):28-33.

Bolognesi C, Carrasquilla G, Volpi S, Solomon KR, Marshall EJ. (2009) Biomonitoring of genotoxic risk in agricultural workers from five colombian regions:association to occupational exposure to glyphosate. J Toxicol Environ Health A.2009;72(15-16):986-97.

Chaufan G, Coalova I, Molina Mdel C. (2014) Glyphosate commercial formulation causes cytotoxicity, oxidative effects, and apoptosis on human cells: differences with its active ingredient. Int J Toxicol. 2014 Jan;33(1):29-38.

DBrant, Jeanne (2014) GMOs, Gut Flora, the Shikimate Pathway and Cytochrome Dysregulation. Nutritional Perspectives: Journal of the Council on Nutrition . Jan, Vol. 37 Issue 1, p5-12. 8p.

Defarge N, Mesnage R, Gress S, Sralini GE. (2012) Letter to the editor: developmental and reproductive outcomes of roundup and glyphosate in humans and animals. J Toxicol Environ Health B Crit Rev. 2012;15(7):433-7

Deo SP, Shetty P. (2012) Accidental chemical burns of oral mucosa by herbicide. JNMA J Nepal Med Assoc. Jan-Mar;52(185):40-2.

Elie-Caille C, Heu C, Guyon C, Nicod L. (2010) Morphological damages of a glyphosate-treated human keratinocyte cell line revealed by a micro- to nanoscale microscopic investigation. Cell Biol Toxicol. Aug;26(4):331-9.

Vincent F Garry, Mary E Harkins, Leanna L Erickson, Leslie K Long-Simpson, Seth E Holland, and Barbara L Burroughs (2002) Birth defects, season of conception, and sex of children born to pesticide applicators living in the Red River Valley of Minnesota, USA. Environ Health Perspect. June; 110(Suppl 3): 441449.

Gasnier C, Dumont C, Benachour N, Clair E, Chagnon MC, Sralini GE (2009) Glyphosate-based herbicides are toxic and endocrine disruptors in human cell lines. Toxicology. Aug 21;262(3):184-91.

Gasnier C, Benachour N, Clair E, Travert C, Langlois F, Laurant C, Decroix-Laporte C, Sralini GE. (2010) Dig1 protects against cell death provoked by glyphosate-based herbicides in human liver cell lines. J Occup Med Toxicol. 2010 Oct 27;5:29

Jasmine George and Yogeshwer Shukla (2013) Emptying of Intracellular Calcium Pool and Oxidative Stress Imbalance Are Associated with the Glyphosate-Induced Proliferation in Human Skin Keratinocytes HaCaT Cells ISRN Dermatol. 2013; 825180.!po=65.3846

Heu C, Berquand A, Elie-Caille C, Nicod L. (2012) Glyphosate-induced stiffening of HaCaT keratinocytes, a Peak Force Tapping study on living cells. J Struct Biol. Apr;178(1):1-7.

Celine Heu, Celine Elie-Caille, Virginie Mougey, Sophie Launay, Laurence Nicod (2012) A step further toward glyphosate-induced epidermal cell death: Involvement of mitochondrial and oxidative mechanisms Environmental Toxicology and Pharmacology Volume 34, Issue 2, September 2012, Pages 144153

Hokanson R, Fudge R, Chowdhary R, Busbee D. (2007) Alteration of estrogen-regulated gene expression in human cells induced by the agricultural and horticultural herbicide glyphosate. Hum Exp Toxicol. Sep;26(9):747-52.

Malin Hultberg (2007) Cysteine turnover in human cell lines is influenced by glyphosate Environmental Toxicology and Pharmacology Volume 24, Issue 1, July, Pages 1922

Jayasumana, Channa; Gunatilake, Sarath; Senanayake, Priyantha. (2014) Glyphosate, Hard Water and Nephrotoxic Metals: Are They the Culprits Behind the Epidemic of Chronic Kidney Disease of Unknown Etiology in Sri Lanka? Int. J. Environ. Res. Public Health 11, no. 2: 2125-2147.

Koller VJ, Fürhacker M, Nersesyan A, Mišík M, Eisenbauer M, Knasmueller S. (2012) Cytotoxic and DNA-damaging properties of glyphosate and Roundup in human-derived buccal epithelial cells. Arch Toxicol. May;86(5):805-13.

Krüger, M., Schledorn, P., Schrödl, W., Hoppe, H. W., & Lutz, W. (2014). Detection of Glyphosate Residues in Animals and Humans. J Environ Anal Toxicol, 4(210), 2161-0525.

Lioi MB, Scarfi MR, Santoro A, Barbieri R, Zeni O, Salvemini F, Di Berardino D, Ursini MV (1998) Cytogenetic damage and induction of pro-oxidant state in human lymphocytes exposed in vitro to gliphosate, vinclozolin, atrazine, and DPX-E9636. Environ Mol Mutagen. 32(1):39-46.

Mariager TP, Madsen PV, Ebbehøj NE, Schmidt B, Juhl A. (2013) Severe adverse effects related to dermal exposure to a glyphosate-surfactant herbicide. Clin Toxicol (Phila). 2013 Feb;51(2):111-3.

Martinez A, Reyes I, Reyes N (2007) Cytotoxicity of the herbicide glyphosate in human periphera lblood mononuclear cells. Biomedica. Dec;27(4):594-604.

Daniela Merlotti, Luigi Gennari, Konstantinos Stolakis, and Ranuccio Nuti (2011) Aromatase Activity and Bone Loss in Men. Journal of Osteoporosis

Volume 2011, Article ID 230671, 11 pages

R Mesnage, E Clair, J Spiroux de Vendmois, G-E Sralini (2010) Two cases of birth defects overlapping Stratton-Parker syndrome after multiple pesticide exposure Occup Environ Med;67:359

Robin Mesnage, Christian Moesch, Rozenn Le Grand, Guillaume Lauthier, Jol Spiroux de Vendmois, Steeve Gress, Gilles-Eric Sralini (2012) Glyphosate Exposure in a Farmers Family Journal of Environmental Protection, 3, 1001-1003

Mesnage R, Bernay B, Sralini GE. (2012) Ethoxylated adjuvants of glyphosate-based herbicides are active principles of human cell toxicity. Toxicology. Sep 21. pii: S0300-483X(12)00345-9.

R. Mesnage, E. Clair, S. Gress, C. Then, A. Szkács, G.-E. Sralini (2013) Cytotoxicity on human cells of Cry1Ab and Cry1Ac Bt insecticidal toxins alone or with a glyphosate-based herbicide Journal of Applied Toxicology Volume 33, Issue 7, pages 695699, July

Robin Mesnage, Nicolas Defarge, Jol Spiroux de Vendmois, and Gilles-Eric Sralini (2013) Major pesticides are more toxic to human cells than their declared active principles BioMed Research International

Monroy CM, Corts AC, Sicard DM, de Restrepo HG. (2005) [Cytotoxicity and genotoxicity of human cells exposed in vitro to glyphosate]. Biomedica. Sep;25(3):335-45.

Wendy A Morley, Stephanie Seneff (2014) Diminished brain resilience syndrome: A modern day neurological pathology of increased susceptibility to mild brain trauma, concussion, and downstream neurodegeneration. Surg Neurol Int, 5:97;year=2014;volume=5;issue=1;spage=97;epage=97;aulast=Morley

Sara Mostafalou, Mohammad Abdollahi (2013) Pesticides and human chronic diseases: Evidences, mechanisms, and perspectives. Toxicology and Applied Pharmacology Volume 268, Issue 2, 15 April 2013, Pages 157177

Teresinha de Jesus C. Neiva; Ana Carolina R. Moraes; Rafaella SchwyzerI; Cidnia de Lourdes Vituri; Tania Rubia F. Rocha; Diana M. Fries; Márcio A. Silva; Aloisio Luiz Benedetti (2010) In vitro effect of the herbicide glyphosate on human blood platelet aggregation and coagulation Rev. Bras. Hematol. Hemoter. vol.32 no.4

Paz-y-Miño, C.,Sánchez, M.E., Arvalo, M., Muñoz,M.J., Witte, T., De-la-Carrera, G.O., Leone, P.E. (2007) Evaluation of DNA damage in an Ecuadorian population exposed to glyphosate. Genetics and Molecular Biology 30,456-460.

Potrebi O, Jovi-Stosi J, Vucini S, Tadi J, Radulac M (2009) [Acute glyphosate-surfactant poisoning with neurological sequels and fatal outcome]. Vojnosanit Pregl. Sep;66(9):758-62.

Potti, A. and I. Sehgal, Exposure to pesticides increases levels of uPA and uPAR in pre- malignant human prostate cells. Environ Toxicol Pharmacol, 2005. 19(2): p. 215-9.

Poulsen, M.S., Rytting, E., Mose, T., Knudsen, L.E. (2000) Modeling placental transport : correlation of invitro BeWo cell permeability and exvivo human placental perfusion. Toxicol. in Vitro 23,13801386.

Richard S, Moslemi S, Sipahutar H, Benachour N, Seralini GE. (2005) Differential effects of glyphosate and roundup on human placental cells and aromatase. Environ Health Perspect. Jun;113(6):716-20.

Roberts DM, Buckley NA, Mohamed F, Eddleston M, Goldstein DA, Mehrsheikh A, Bleeke MS, Dawson AH. (2010) A prospective observational study of the clinical toxicology of glyphosate-containing herbicides in adults with acute self-poisoning. Clin Toxicol (Phila). Feb;48(2):129-36.

Rull RP, Ritz B, Shaw GM. (2004) Neural tube defects and maternal residential proximity to agricultural pesticide applications. .Epidemiology. July, 15(4): S188. 33.

Rull RP, Ritz B, Shaw GM. (2006) Neural tube defects and maternal residential proximity to agricultural pesticide applications. Am J Epidemiol. Apr 15; 163(8): 743-753.

Salvagni, J., R.Z. Ternus, and A.M. Fuentefria. (2011) Assessment of the Genotoxic Impact of Pesticides on Farming Communities in the Countryside of Santa Catarina State, Brazil. Genetics and Molecular Biology 34, no. 1 : 122-26.

Anthony Samsel and Stephanie Seneff (2013) Glyphosates Suppression of Cytochrome P450 Enzymes and Amino Acid Biosynthesis by the Gut Microbiome: Pathways to Modern Diseases Entropy 2013, 15(4), 1416-1463

Sato C, Kamijo Y, Yoshimura K, Ide T. (2011) Aseptic meningitis in association with glyphosate-surfactant herbicide poisoning. Clin Toxicol (Phila). Feb;49(2):118-20.

Savitz, D.A., Arbuckle, T., Kaczor, D., Curtis, K.M. 1997. Male pesticide exposure and pregnancy outcome. Am. J. Epidemiol. 146, 10251036.

Slager RE, Simpson SL, Levan TD, Poole JA, Sandler DP, Hoppin JA. (2010) Rhinitis associated with pesticide use among private pesticide applicators in the agricultural health study. J Toxicol Environ Health A. ;73(20):1382-93.

Thongprakaisang S, Thiantanawat A, Rangkadilok N, Suriyo T, Satayavivad J. (2013) Glyphosate induces human breast cancer cells growth via estrogen receptors. Food Chem Toxicol. Sep;59:129-36.


A J De Roos, S Zahm, K Cantor, D Weisenburger, F Holmes, L Burmeister, and A Blair (2003) Integrative assessment of multiple pesticides as risk factors for non-Hodgkins lymphoma among men Occup Environ Med. September; 60(9): e11.

De Roos AJ, Blair A, Rusiecki JA, Hoppin JA, Svec M, Dosemeci M, Sandler DP, Alavanja MC. (2005) Cancer incidence among glyphosate-exposed pesticide applicators in the Agricultural Health Study. Environ Health Perspect. Jan;113(1):49-54.

Eriksson M, Hardell L, Carlberg M, Akerman M. (2008) Pesticide exposure as risk factor for non-Hodgkin lymphoma including histopathological subgroup analysis. Int J Cancer. Oct 1;123(7):1657-63

Hardell, L., Eriksson ,M.A. (1999) Case-control study of non-Hodgkin lymphoma and exposure to pesticides. Cancer 85,135360.

Hardell L, Eriksson M, Nordstrom M. (2002) Exposure to pesticides as risk factor for non-Hodgkins lymphoma and hairy cell leukemia: pooled analysis of two Swedish case-control studies. Leuk Lymphoma. May;43(5):1043-9

Schinasi L, Leon ME (2014) Non-hodgkin lymphoma and occupational exposure to agricultural pesticide chemical groups and active ingredients: a systematic review and meta-analysis. Int J Environ Res Public Health. Apr 23;11(4):4449-527.


Barbosa ER, Leiros da Costa MD, Bacheschi LA, Scaff M, Leite CC. (2001) Parkinsonism after glycine-derivate exposure. Mov Disord. May;16(3):565-8.

da Costa Mdo D, Gonçalves LR, Barbosa ER, Bacheschi LA. (2003) [Neuroimaging abnormalities in parkinsonism: study of five cases]. Arq Neuropsiquiatr. Jun;61(2B):381-6.

Wang G, Fan XN, Tan YY, Cheng Q, Chen SD. (2011) Parkinsonism after chronic occupational exposure to glyphosate. Parkinsonism Relat Disord. Jul;17(6):486-7.