CRUCIAL PAPERS 46 and 47: Damage to rats from MON810 (Ajeeb YG) in 3-month study
Date Added to website 14th January 2014
These two papers from Egyptian researchers show that there are substantial and significant differences which appear in animals fed on a Monsanto 810 variety called Ajeeb YG (for Yieldguard) and in those fed on normal Ajeeb grains. Histopathologocal changes were apparent in rats after 91 days, as were organ changes, and other morphological and biochemical changes. Once again, the evidence stacks up of actual harm to mammals that are fed on GMO corn. When is somebody going to sit up and take notice?
Histopathological Changes in Some Organs of Male Rats Fed on Genetically Modified Corn
(Ajeeb YG) by El-Shamei, Z. S., Gab-Alla, A.A., Shatta, A. A, Moussa, E. A. and Rayan, A. M. ammrayan@yahoo.com
Abstract:
Ajeeb YG is a genetically modified (GM) insect resistant corn produced by incorporated the MON 810 (Monsanto) borer resistance trait in the best corn germplasm Ajeeb. The safety of Ajeeb YG corn was assessed by comparison of toxicology response variables in rats consuming diets containing Ajeeb YG with those containing Ajeeb corn grains. Corn grains from Ajeeb YG or Ajeeb were incorborated into rodent diets at 30% concentrations administered to rats (n= 10/group) for 91 days. An additional negative control group of rats (n= 10/group) were fed AIN93G diets. Rats fed on GM corn showed histopathological changes. Liver displayed cytoplasmic vacuolation of centrolobular hepatocytes and fatty degeneration of hepatocytes. Kidneys showed congestion of renal blood vessels and cystic dilatation of renal tubules. Testes revealed necrosis and desquamation of spermatogoneal germ cells lining seminiferous tubules. Spleen showed slight lymphocytic depletion and splenic congestion. Small intestine showed hyperplasia, hyperactivation of mucous secretory glands and necrosis of intestinal villi were detected. Due to these observations, we suggest that the risk of GM crops cannot be ignored and deserves further investigations in order to identify possible long-term effects, if any, of GM food consumption that might help in the post market surveillance.
[El-Shamei, Z. S., Gab-Alla, A.A., Shatta, A. A, Moussa, E. A. and Rayan, A. M. Histopathological Changes in Some Organs of Male Rats Fed on Genetically Modified Corn (Ajeeb YG). J Am Sci 2012;8(10): 684-696]. (ISSN: 1545-1003). http://www.jofamericanscience.org. 93
Morphological and Biochemical Changes in Male Rats Fed on Genetically Modified Corn
(Ajeeb YG) by Gab-Alla, A. A., El-Shamei, Z.S., Shatta, A.A., Moussa, E.A., and Rayan, A.M. ammrayan@yahoo.com
Abstract :
This study was designed to evaluate the safety of genetically modified (GM) corn (Ajeeb YG). Corn grains from Ajeeb YG or its control (Ajeeb) were incorporated into rodent diets at 30% concentrations administered to rats (n= 10/group) for 45 and 91 days. An additional negative control group of rats (n= 10/group) was fed AIN93G diets. General conditions were observed daily, total body weights were recorded weekly. At the termination of the study periods, some visceral organs (heart, liver, kidneys, testes and spleen) and serum biochemistry were measured. The data showed several statistically significant differences in organs/body weight and serum biochemistry between the rats fed on GM and/or Non-GM corn and the rats fed on AIN93G diets. In general, GM corn sample caused several changes by increase or decrease organs/body weight or serum biochemistry values. This indicates potential adverse health/toxic effects of GM corn and further investigations still needed.
[Gab-Alla, A. A., El-Shamei, Z. S., Shatta, A. A., Moussa, E. A., and Rayan, A. M. Morphological and Biochemical Changes in Male Rats Fed on Genetically Modified Corn (Ajeeb YG). J Am Sci 2012;8(9):1117- 1123]. (ISSN: 1545-1003). http://www.jofamericanscience.org. 152