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Glyphosate is toxic to dairy cows

Date Added to website 27th August 2015

Glyphosate is toxic to dairy cows

Krüger M, Schrödl W, Neuhaus J, Shehata AA (2013) Field Investigations of Glyphosate in Urine of Danish Dairy Cows. J Environ Anal Toxicol 3: 186.

In the present study, thirty dairy cows from each of eight Danish dairy farms were investigated for excretion of glyphosate in urine. Blood serum parameters indicative of cytotoxicity as alkaline phosphatase (AP), glutamate dehydrogenase (GLDH), glutamate oxaloacetate transaminase (GOT), creatinine kinase CK), nephrotoxicity, (urea, creatine), cholesterol and the trace elements as manganese (Mn), cobalt (Co), selenium (Se), copper (Cu) and zinc (Zn) were investigated. All cows excreted glyphosate in their urine but in varying concentrations. Increased levels of GLDH, GOT and CK in cows from all farms demonstrate a possible effect of glyphosate on liver and muscle cells. High urea levels in some farms could be due to nephrotoxicity of glyphosate. Also the unexpected very low levels of Mn and Co were observed in all animals which could be explained due to a strong mineral chelating effect of glyphosate. In contrast the mean levels of Cu, Zn and Se were within the normal reference range. In conclusion, this study gives the first documentation to which extent Danish dairy cattle are exposed to Glyphosate and its impact on blood parameters.

All cows investigated at the eight Danish dairy farms excreted glyphosate in their urine at significant different amounts between the farms. We found increased blood serum levels of parameters indicative for cytotoxicity like GLDH, GOT, and CK and the lipid profile marker cholesterol in cows at all farms and high urea levels in half of the farm animals. Correlations between glyphosate and some of the measured blood serum parameters to CK (R= 0.135), Se (R=- 0.188), Co (R= -0,403) and Zn (R=0,175) demonstrate that glyphosate is toxic to the normal metabolism of dairy cows. This study gives the first documentation to which extent Danish dairy cattle are exposed to glyphosate and its impact on different blood parameters.