GM Free Cymru

Articles citing adverse health effects from GMOs

Date Added to website 9th August 2015


=================
Articles citing adverse health effects from GMOs
=========================
Comment: In this very perceptive article by Sheldon Krimsky. Table 2 details 26 articles which demonstrate the manner in which GMOs can have adverse health effects when used in controlled experiments / animal feeding studies. Note that these studies relate to GMOs, and not to glyphosate or other chemicals used in conjunction with RR and other crops. On the other hand, we cannot rule out the possibility that some of the observed effects relate to glyphosate and other residues, because it is not always possible for researchers to obtain certified feeds which are known to be completely clear of agrichemicals.

======================
An Illusory Consensus behind GMO Health Assessment
=========================

Sheldon Krimsky

Science, Technology, & Human Values 1-32 DOI: 10.1177/0162243915598381

Abstract

Prominent scientists and policymakers assert with confidence that there is no scientific controversy over the health effects of genetically modified organisms (GMOs)—that genetically modified crops currently in com- mercial use and those yet to be commercialized are inherently safe for human consumption and do not have to be tested. Those who disagree are cast as ‘‘GMO deniers.’’ This article examines scientific reviews and papers on GMOs, compares the findings of professional societies, and discusses the treatment of scientists who have reported adverse effects in animal feeding experiments. This article concludes by exploring the role that politics and corporate interests have had in distorting an honest inquiry into the health effects of GMO crops.

Table 2.
26 Articles Citing Adverse Effects or Uncertainties on the Health Effects of GMOs. (mostly animal feeding studies)

Fares, N. H., and A. K. El-Sayed. 1998. ‘‘Fine Structure Changes in the Ileum of Mice Fed on Endotoxin-treated Potatoes and Transgenic Potatoes.’’ Natural Toxins 6 (6): 219-33.

Ewen, S. W. B., and A. Pusztai. 1999. ‘‘Effects of Diets Containing Genetically Modified Potatoes Expressing Galanthus nivalis Lectin on Rat Small Intestine.’’ Lancet 354 (9187): 1353-54.

Birch, A. N. E., I. E. Geoghegan, M. E. N. Majerus, J. W. McNicol, C. A. Hackett, A. M. R. Gatehouse, and J. A. Gatehouse. 1999. ‘‘Tri-trophic Interactions Involving Pest Aphids, Predatory 2-spot Ladybirds and Transgenic Potatoes Expressing Snowdrop Lectin for Aphid Resistance.’’ Molecular Breeding 5 (1): 75-83.

Malatesta, M., C. Caporaloni, S. Gavaudan, M. B. L. Rocchi, S. Serafini, C. Tiberi, and G. Gazzanelli. 2002. ‘‘Ultrastructural Morphometrical and Immunocytochemical Analysis of Hepatocyte Nuclei from Mice Fed on Genetically Modified Soybean.’’ Cell Structure Function 27 (5): 173-80.

Malatesta, M., C. Caporaloni, L. Rossi, S. Battistelli, M. B. L. Rocchi, F. Tonucci, and G. Gazzanelli. 2002. ‘‘Ultrastructural Analysis of Pancreatic Acinar Cells from Mice Fed on Genetically Modified Soybean.’’ Journal of Anatomy 201 (5): 409-15.

Malatesta, M., M. Biggiogera, E. Manuali, M. B. L. Rochhi, B. Baldelli, and G. Gazzanelli. 2003. ‘‘Fine Structural Analyses of Pancreatic Acinar Cell Nuclei from Mice Fed on Genetically Modified Soybean.’’ European J. Histochemistry 47 (4): 385-99.

Pryme, I. F., and Rolf Lembcke. 2003. ‘‘In Vivo Studies on Possible Health Consequences of Genetically Modified Food and Feed—with Particular Regard to Ingredients Consisting of Genetically Modified Plant Materials.’’ Nutrition and Health 17 (1): 1-8.

Vecchio, L., B. Cisterna, M. Malatesta, T. Martin, and B. Biggiogera. 2004. ‘‘Ultrastructural Analysis of Testes from Mice Fed on Genetically Modified Soybean.’’ European Journal of Histochemistry 48 (4): 449-54.

Prescott, V. E., P. M. Campbell, A. Moore, J. Mattes, M. E. Rothenberg, P. S. Foster, T. J. Higgins, and S. P. Hogan. 2005. ‘‘Transgenic Expression of Bean Alpha- amylase Inhibitor in Peas Results in Altered Structure and Immunogenicity.’’ Journal of Agriculture Food & Chemistry 53 (23): 9023-30.

Tudisco, R., F. Lombardi, F. Bovera, D. dˇAngelo, M. I. Cutrignelli, V. Mastellone, V. Terzi, L. Avallone, and F. Infascelli. 2006. ‘‘Genetically Modified Soy Bean in Rabbit Feeding: Detection of DNA Fragments and Evaluation of Metabolic Effects by Enzymatic Analysis.’’ Animal Science 82 (2): 193-99.

Ermakova, I. V. 2006. ‘‘Genetically Modified Soy Leads to the Decrease of Weight and High Mortality of Rat Pups of the First Generation. Preliminary Studies.’’ EcosInform 1:4-9. (in Russian)

Sagstad, A., M. Sanden, Ø. Haugland, A. C. Hansen, P. A. Olsvik, and G. I. Hemre. 2007. ‘‘Evaluation of Stress- and Immune-response Biomarkers in Atlantic Salmon for Different Levels of Bt Maize.’’ Journal of Fish Diseases 30 (4): 201-12.

Seralini, G.-E., D. Cellier, and J. S. de Vendomois. 2007. ‘‘New Analysis of Rat Feeding Study with GM Maize Reveals Signs of Hepatorenal Toxicity.’’ Archives of Environmental Contaminant Toxicology 52 (4): 596-602.

Malatesta, M., F. Boraldi, G. Annovi, Beatrice Baldelli, Serafina Battistelli, Marco Biggiogera, and Daniela Quaglino. 2008. ‘‘A Long-term Study on Female Mice Fed on a Genetically Modified Soybean: Effects on Liver Ageing.’’ Histochemistry Cell Biology 130 (5): 967-77.

Finamore, A., M. Roselli, S. Britti, G. Monastra, R. Ambra, A. Turrini, and E. Mengheri. 2008. ‘‘Intestinal and Peripheral Immune Response to MON810 Maize Ingestion to Weaning and Old Mice.’’ Journal of Agriculture Food & Chemistry 56 (23): 11533-39.

Velimirov, A., C. Binter, and J. Zentek. 2008. ‘‘Biological Effects of Transgenic Maize NK 603xMON810 Fed in Long Term Reproduction Studies in Mice.’’ Forschungsberichte de Sektion IV Band 3/2008, 105. Vienna, Austria. Accessed July 22, 2015. http://www.biosicherheit.de/pdf/aktuell/zentek_studie_2008.pdf.

Kilic, A., and M. T. Akay. 2008. ‘‘A Three Generation Study with Genetically Modified Bt Corn in Rats: Biochemical and Histopathological Investigation.’’ Food & Chemical Toxicology 46 (3): 1164-70.

Cisterna, B., F. Flach, L. Vecchio, S. M. L. Barabino, S. Battistelli, T. E. Martin, M. Malatesta, and M. Biggiogera. 2008. ‘‘Can a Genetically-modified Organism- containing Diet Influence Embryo Development? A Preliminary Study on Pre- implantation Mouse Embryos.’’ European Journal of Histochemistry 52 (4): 263-67.

Bøhn, T., R. Primicerio, D. O. Hessen, and T. Traavik. 2008. ‘‘Reduced Fitness of Daphnia Magna Fed a Bt Transgenic Maize Variety.’’ Archives of Environmental Contamination and Toxicology 55 (4): 584-92.

Trabalza-Marinucci, M., E. Chiaradia, G. Brandi, C. Rondini, L. Avellini, C. Giammarini, S. Costarelli, G. Acuti, C. Orlandi, and G. Filippini. 2008. ‘‘A Three Year Longitudinal Study on the Effects of a Diet Containing Genetically Modified Bt176 Maize on the Health Status and Performance on Sheep.’’ Livestock Science 113 (2-3): 178-90.

Sissener, N. H., M. Sanden, A. M. Bakke, A. Krogdahl, and G. I. Hemre. 2009. ‘‘A Long Term Trial with Atlantic Salmon (Salmo salar L.) Fed Genetically Modified Soy; Focusing General Health and Performance before, during and after the Parr– smolt Transformation.’’ Aquaculture 294 (1-2): 108-17.

Atremis, D., and I. S. Arvantioyannis. 2009. ‘‘Health Risks of Genetically Modified Foods.’’ Critical Reviews in Food Science and Nutrition 49 (2): 164-75.
de Vendoˆmois, J. Spiroux, F. Roullier, D. Cellier, and Gilles-Eric Se ́ralini. 2009. ‘‘A Comparison of the Effects of Three GM Corn Varieties on Mammalian Health.’’ Int. J. Biological Sciences 5 (7): 706-26.

Aris, A., and S. Leblanc. 2011. ‘‘Maternal and Fetal Exposure to Pesticides Associated to Genetically Modified Foods in Eastern Township of Quebec, CA.’’ Reproductive Toxicology 31 (4): 528-33.

Se ́ralini, G.-E., E. Clair, R. Mesnage, Steeve Gress, Nicolas Defarge, Manuela Malatesta, Didier Hennequin, and Joe ̈l Spiroux de Vendoˆmois. 2012. ‘‘Long Term Toxicity of a Roundup Herbicide and a Roundup-tolerant Genetically Modified Maize.’’ Food and Chemical Toxicology 50:4221-31 (retracted 2014) republished in Environmental Sciences Europe 26:1-17 (2014).

Carman, J. A., H. R.Vlieger, L. J. Ver Steeg, V. Sneller, G. Robinson, C. Clinch-Jones, J. Haynes, and J. Edwards. 2013. ‘‘A Long-term Toxicology Study on Pigs Fed a Combined Genetically Modified Soy and Maize Diet.’’ Journal of Organic Systems 8 (1): 38-54.