Immediate Release 6th November 2015
Breaking news: 35-year cover-up of glyphosate / cancer link exposed
For the past 35 years Monsanto has known of the link between glyphosate and cancer, but has systematically worked to cover it up through scientifically fraudulent methods in its safety testing research programme. This is the most significant conclusion to be drawn from a new research paper (1) published in the Journal of Biological Physics and Chemistry and now available online.
For the first time the authors, Anthony Samsel and Stephanie Seneff, present in tabulated form the data contained in secret Monsanto studies conducted in the period 1980 - 1990 which showed unequivocally that animals exposed to very small quantities of glyphosate in their food supply developed tumorigenic growth in multiple organs. Both Monsanto and the American EPA knew of these and other deleterious effects, but the EPA agreed to refer to these early studies as "trade secrets" and prevented public scrutiny. The results were considered inconvenient, and so they were ignored. To make matters worse, the EPA then agreed to further Monsanto-sponsored studies which used inappropriate control group data to create "experimental noise" and to mask carcinogenic and other effects in the animal test groups. Other fraudulent practices have also been subsequently revealed, including the non-reporting of test group deaths, the fabrication of data tables, and the falsification of experimental data (2).
Dr Samsel is the first independent researcher to have been given access to the full Monsanto / EPA dossier of research reports, and the new paper itemises the key research findings in these early papers and presents a number of detailed appendices of the results.
The authors conclude: "In this paper, we have reviewed the research literature on glyphosate and on the biological processes associated with cancer, and we have provided strong evidence that glyphosate is likely contributing to the increased prevalence of multiple types of cancer in humans. Monsanto’s own early studies revealed some trends in animal models that should not have been ignored. Forty years of glyphosate exposure have provided a living laboratory where humans are the guinea pigs and the outcomes are alarmingly apparent."
In their Abstract (3), the authors say: "Glyphosate has a large number of tumorigenic effects on biological systems, including direct damage to DNA in sensitive cells, disruption of glycine homeostasis, succinate dehydrogenase inhibition, chelation of manganese, modification to more carcinogenic molecules such as N-nitrosoglyphosate and glyoxylate, disruption of fructose metabolism, etc. Epidemiological evidence supports strong temporal correlations between glyphosate usage on crops and a multitude of cancers."
Speaking on the day of publication, Dr Samsel said: "Glyphosate is a reactive product that causes damage at the molecular level. Chemicals that disrupt the microbiome and immune function do not belong in our food supply . To allow any living creature exposure to such a product is, in my opinion, poor judgment by government agencies and serves only to benefit the purses of corporations and their investors. Future generations will judge our actions or lack thereof and surely condemn those who repeat the errors of the past."
Speaking for GM-Free Cymru, Dr Brian John says: "In 1981 both Monsanto and the EPA were already aware of malignant tumours and pre-cancerous conditions in the test animals which were fed small doses of glyphosate in the secret feeding experiments (4). Although concerns were expressed at the time by EPA committees, these concerns were later suppressed while Monsanto was allowed to bring forward a range of cynically manipulated and fraudulent studies purporting to show that glyphosate was harmless (2). None of these studies has been made available for independent examination. That is a scandal in itself. There has been a protracted and cynical cover-up in this matter. Monsanto and the EPA have been fully aware of the carcinogenic potential of glyphosate for at least 35 years. If they had acted in a precautionary fashion back then, instead of turning a blind eye to scientific malpractice, glyphosate would never have been licensed, and hundreds of thousands of lives might have been saved."
(1) Glyphosate, pathways to modern diseases IV: cancer and related pathologies
Anthony Samsel and Stephanie Seneff.
Journal of Biological Physics and Chemistry 15 (2015), 121–159.
(2) Wikipedia 2012: Internal EPA Memos Document Fraud
1983 EPA Scientist on EPA's public stance: “Our viewpoint is one of protecting the public health when we see suspicious data.” Unfortunately, EPA has not taken that conservative viewpoint in its assessment of glyphosate’s cancer causing potential.”
“There are no studies available to NCAP evaluating the carcinogenicity of Roundup or other glyphosate-containing products. Without such tests, the carcinogenicity of glyphosate-containing products is unknown.”
“Tests done on glyphosate to meet registration requirements have been associated with fraudulent practices.”
“Countless deaths of rats & mice are not reported.”
“Data tables have been fabricated”
“There is a routine falsification of data”
Glyphosate is the active ingredient in the pervasive herbicide, Roundup, and its usage, particularly in the United States, has increased dramatically in the last two decades, in step with the widespread adoption of Roundup®-Ready core crops. The World Health Organization recently labelled glyphosate as “probably carcinogenic.” In this paper, we review the research literature, with the goal of evaluating the carcinogenic potential of glyphosate. Glyphosate has a large number of tumorigenic effects on biological systems, including direct damage to DNA in sensitive cells, disruption of glycine homeostasis, succinate dehydrogenase inhibition, chelation of manganese, modification to more carcinogenic molecules such as N-nitrosoglyphosate and glyoxylate, disruption of fructose metabolism, etc. Epidemiological evidence supports strong temporal correlations between glyphosate usage on crops and a multitude of cancers that are reaching epidemic proportions, including breast cancer, pancreatic cancer, kidney cancer, thyroid cancer, liver cancer, bladder cancer and myeloid leukaemia. Here, we support these correlations through an examination of Monsanto’s early studies on glyphosate, and explain how the biological effects of glyphosate could induce each of these cancers. We believe that the available evidence warrants a reconsideration of the risk/benefit trade-off with respect to glyphosate usage to control weeds, and we advocate much stricter regulation of glyphosate.
(4) The results tabulated in the new paper were foreshadowed in a special report from GM-Free Cymru published in April 2017:
At that time, there was relatively limited access to EPA dossiers. The new paper by Samsel and Seneff fills in the gaps, by presenting and analysing the censored or secret Monsanto data.